Alumni

Former Chair of Bioprocess Engineering (until 2021)

Scientific focus

  • selective fractionation and concentration of complex raw materials
  • structure design in food
  • bioprocess and biofunctionality
  • analytical techniques for the characterization of food and bio-systems

References
Kulozik UM: “Structuring Dairy Products by Means of Processing and Matrix Design”. In: Food Materials Science – Principles and Practice. Editor: Aguilera JM,  Lillford PJ. New York: Springer Science and Business Media, 2008 Abstract

Kulozik UM: “Verfahrenstechnik kontinuierlicher Fermentationen – dargestellt am Beispiel der Milchsäure- und Biomassegewinnung im Rohrfermenter“. Düsseldorf: Verlag des Vereins deutscher Ingenieure (VDI), 1992.Abstract

Kulozik UM: „Einflüsse auf die Permeation von Wasser und gelösten Stoffen sowie auf den Deckschichtabtrag bei der Umkehrosmose“. Düsseldorf: Verlag des Vereins deutscher Ingenieure (VDI), 1986.Abstract

Former Chair of Microbial Ecology (until 2021)
Director of ZIEL 2003-2014

Scientific focus

  • Microbioal ecology
  • Food safety research on the ecology of food borne pathogens, e.g. Escherichia coli (EHEC)
  • Taxonomy and evolution: biodiversity of food borne microorganisms with focus on raw milk

References
link to full list

Landstorfer R, Simon S, Schober S, Keim D, Scherer S, Neuhaus K (2014) Comparison of strand-specific transcriptomes of enterohemorrhagic Escherichia coli O157:H7 EDL933 (EHEC) under eleven different environmental conditions including radish sprouts and cattle feces. BMC Genomics 15:353, DOI: 10.1186/1471-2164-15-353

von Neubeck M, Baur C, Krewinkel M, Stoeckel M, Kranz B, Stressler T, Fischer L, Hinrichs J, Scherer S, Wenning M (2015) Biodiversity of refrigerated raw milk microbiota and their enzymatic spoilage potential. Int J Food Microbiol 211:57-65

Neuhaus K, Landstorfer R, Simon S, Schober S, Wright P, Smith C, Backofen R, Wecko R, Keim D, Scherer S (2017) Differentiation of ncRNAs from small mRNAs in Escherichia coli O157:H7 EDL933 (EHEC) by combined RNAseq and RIBOseq – ryhB encodes the regulatory RNA RyhB and a peptide, RyhP. BMC Genomics 8:216 DOI: 10.1186/s12864-017-3586-9

Technische Universität München
Lehrstuhl für Biotechnologie der Nutztiere
TUM School of Life Sciences

Website

Scientific focus
- development of genetically engineered pigs for translational research 
- Genetic and epigenetic analysis
- Xenotransplantation

References
Flisikowska, T., Merkl, C., Landmann, T, Eser, S., Rezaei, N., Cui, X., Kurome, M., Zakhartchenko, V., Kessler, B., Wieland, H., Rottmann, O., Schmid, R.M., Schneider, G., Kind, A., Wolf, E., Saur, D. and Schnieke, A. (2012). A porcine model of familial adenomatous polyposis. Gastroenterology 143, 1173-1175.

Saalfrank, A., Janssen, K-P., Ravon, M., Flisikowski, K., Eser, S., Steiger, K., Flisikowska, T., Müller-Fliedner, P., Schulze, E., Brönner, C., Gnann, A., Kappe, E., Böhm, B., Schade, B., Certa, U., Saur, D., Esposito, I., Kind, A. and Schnieke. A. (2016). A porcine model of osteosarcoma. Oncogenesis 5, e210. doi: 10.1038/oncsis.2016.19.

Fischer, K., Kraner-Scheiber, S., Petersen, B., Rieblinger, B., Buermann, A., Flisikowska, T., Flisikowski, K., Christan, S., Edlinger, M., Baars, W., Kurome, M., Zakhartchenko, V., Kessler, B., Plotzki, E., Szczerbal, I., Switonski, M., Denner, J., Wolf, E., Schwinzer, R., Niemann, H., Kind A. and Schnieke A. (2016). Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing. Nature Scientific Reports 6, 29081 doi: 10.1038/srep29081.

Former Chair of intestinal Microbiome

Website

current affiliation:

University of Birmingham
Chair of Microbiome Research
Institute of Microbiology and Infection
e-mail: l.hall.3@bham.ac.uk

Further information:
The Hall lab comprises a multi-disciplinary team that is seeking to understand the molecular aspects of microbiome interactions, at the interface of the gut mucosa. We have a particular focus on the early life developmental window, as pregnancy and infancy, and the microbes that colonise during this time (e.g. Bifidobacterium), coincides with key physiological programming, and is when the foundations of future health and wellbeing are laid down.

My labs research programme is organised into three complimentary themes (i) microbe-diet interactions, (ii) colonisation resistance, and (iii) microbiota-host crosstalk. These themes are interlinked by large longitudinal cohort studies, including a preterm infant cohort and a mother-infant dyad cohort. Our clinical studies (and clinical studies lead by other ZIEL members) underpin our wider research activities, which comprise a series of coordinated investigations addressing the mechanistic foundation of microbiome-host interactions in health and disease, with the aim of intervention and therapy development. We collaborate with other ZIEL members to leverage their significant expertise in different disciplines and their innovative model systems.

The lab utilises multi-disciplinary approaches and ZIEL core facilities to answer these key questions including; microbiology (in vitro model-colon systems for complex culturing, molecular microbiology, cultureomics), metabolomics (NMR, M/S), next generation sequencing (RNASeq, 16S rRNA, WGS, metagenomics; both host and microbe), bioinformatics tools, in vivo models (germ-free and infection models) and human studies (infants and adults).