Selected Publications

Ramaboli* MC., Ocvirk* S., Khan Mirzaei M., Eberhart BL., Valdivia-Garcia M., Metwaly A., Neuhaus K., Barker G., Ru J., Nesengani LT., Mahdi-Joest D., Wilson AS., Joni SK., Layman DC., Zheng J., Mandal R., Chen Q., Perez MR., Fortuin S., Gaunt B., Wishart D., Methé B., Haller D., Li JV., Deng L., Swart R., O’Keefe SJD.: Diet changes due to urbanization in South Africa are linked to microbiome and metabolome signatures of Westernization and colorectal cancer. Nat Commun 15, 3379 (2024). 

Wortmann E., Osswald A., Wylensek D., Kuhls S., Coleman O., Ducarmon Q., Liang W., Treichel N., Schumacher F., Volet C., Matysik S., Kleigrewe K., Gigl M., Rohn S., Kleuser B., Liebisch G., Schnieke A., Bernier-Latmani R., Zeller G., Haller D., Flisikowski K., Ocvirk S., Clavel T.: Secondary bile acid production by gut bacteria promotes Western diet-associated colorectal cancer. bioRxiv (2023). doi: doi.org/10.1101/2023.03.17.533140

Ocvirk, S. & O’Keefe, S. J. D.: Dietary fat, bile acid metabolism and colorectal cancer. Semin. Cancer Biol. 73, 347–355 (2021).

Ocvirk, S., Wilson, A. S., Posma, J. M., Li, J. V., Koller, K. R., Day, G. M., Flanagan, C. A., Otto, J. E., Sacco, P. E., Sacco, F. D., Sapp, F. R., Wilson, A. S., Newton, K., Brouard, F., DeLany, J. P., Behnning, M., Appolonia, C. N., Soni, D., Bhatti, F., Methe, B., Fitch, A., Morris, A., Gaskins, H. R., Kinross, J., Nicholson, J. K., Thomas, T. K., O’Keefe, S. J. D.: A prospective cohort analysis of gut microbial co-metabolism in Alaska Native and rural African people at high and low risk of colorectal cancer. Am. J. Clin. Nutr. 111(2), 406–419 (2020).

Katsidzira, L., Ocvirk, S., Wilson, A., Li, J., Mahachi, C. B., Soni, D., DeLany, J., Nicholson, J. K., Zoetendal, E. G., O’Keefe, S. J. D.: Differences in fecal gut microbiota, short-chain fatty acids and bile acids link colorectal cancer risk to dietary changes associated with urbanization among Zimbabweans. Nutr. Cancer. 71, 1313-1324 (2019).